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An inverse correlation between miR-142 and SIRT1 expression was observed in the brains of long-lived aged rhesus macaques (Basova et al., 2022)

The excessive accumulation of iron, which triggers the Fenton reaction and produces reactive oxygen species (ROS), makes this process more severe

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Future therapeutic designs should address the heterogeneity of RA patients metabolic phenotypes, especially metabolic network remodeling in coexisting T2DM

Dial Transplant 1998;27:498-506

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